Alkaloids

Gene	Type	Plant	Family	Medicinal Plant	Natural Product	Description	Genebanks	NCBI Link	Reference
AsCYP76AD1	CYP450	Amaranthus tricolor	Amaranthaceae	Yes	Linoleic Acid,Palmitic Acid,Linolenic Acid,Arachic Acid,Spinasterol	--	NC_080047.1	--	Wang H,Xu D,Wang S, et al. Chromosome-scale Amaranthus tricolor genome provides insights into the evolution of the genus Amaranthus and the mechanism of betalain biosynthesis. DNA Res. 2023;30 (1):. doi:10.1093/dnares/dsac050
LsCYP	CYP450	Lactuca sativa	Asteraceae	Yes	Flavonoids,Ascorbic Acid,Tocopherols,Sesquiterpenoids	cytochrome P450 CYP72A219	LOC111884384	https://www.ncbi.nlm.nih.gov/gene/111884384	--
LsCYP	CYP450	Lactuca sativa	Asteraceae	Yes	Flavonoids,Ascorbic Acid,Tocopherols,Sesquiterpenoids	flavonoid 3',5'-hydroxylase 1	LOC111887493	https://www.ncbi.nlm.nih.gov/gene/111887493	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 72A15	LOC103696920	https://www.ncbi.nlm.nih.gov/gene/103696920	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 72A15	LOC103696921	https://www.ncbi.nlm.nih.gov/gene/103696921	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	alpha-humulene 10-hydroxylase-like	LOC103698752	https://www.ncbi.nlm.nih.gov/gene/103698752	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 CYP72A219	LOC103703363	https://www.ncbi.nlm.nih.gov/gene/103703363	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytokinin hydroxylase	LOC103705582	https://www.ncbi.nlm.nih.gov/gene/103705582	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 734A1	LOC103716275	https://www.ncbi.nlm.nih.gov/gene/103716275	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 704C1	LOC103721382	https://www.ncbi.nlm.nih.gov/gene/103721382	--
PdCYP709B2	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 709B2-like	LOC103696907	https://www.ncbi.nlm.nih.gov/gene/103696907	--
PdCYP709B2-like	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 709B2-like	LOC103698412	https://www.ncbi.nlm.nih.gov/gene/103698412	--
PdCYP711A1	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 711A1	LOC103709562	https://www.ncbi.nlm.nih.gov/gene/103709562	--
PdCYP714C2	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 714C2-like	LOC103697824	https://www.ncbi.nlm.nih.gov/gene/103697824	--
PdCYP714C2	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 714C2-like	LOC103712265	https://www.ncbi.nlm.nih.gov/gene/103712265	--
PdCYP72A15	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 72A15-like	LOC103697368	https://www.ncbi.nlm.nih.gov/gene/103697368	--
PdCYP72A15	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 72A15-like	LOC103698045	https://www.ncbi.nlm.nih.gov/gene/103698045	--
PdCYP734A1	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 734A1	LOC103710957	https://www.ncbi.nlm.nih.gov/gene/103710957	--
PdCYP75B137	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	flavonoid 3'-monooxygenase CYP75B137-like	LOC103702901	https://www.ncbi.nlm.nih.gov/gene/103702901	--
PdCYP78A3	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 78A3-like	LOC103708728	https://www.ncbi.nlm.nih.gov/gene/103708728	--
PdCYP78A5	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 78A5-like	LOC103715852	https://www.ncbi.nlm.nih.gov/gene/103715852	--
PdCYP78A9	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 78A9-like	LOC103699197	https://www.ncbi.nlm.nih.gov/gene/103699197	--
PdCYP79A68	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	tryptophan N-monooxygenase CYP79A68-like	LOC103720455	https://www.ncbi.nlm.nih.gov/gene/103720455	--
PdCYP81Q32	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 81Q32-like	LOC103700914	https://www.ncbi.nlm.nih.gov/gene/103700914	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 704C1	LOC120108100	https://www.ncbi.nlm.nih.gov/gene/120108100	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	abscisic acid 8'-hydroxylase 2	LOC120110976	https://www.ncbi.nlm.nih.gov/gene/120110976	--
PdCYP	CYP450	Phoenix dactylifera	Arecaceae	Yes	Jujube Glycoside,Chrysoeriol-7-glucoside,Pheflolic Acid,Gallic Acid,Ferulic Acid	cytochrome P450 709B2	LOC120112175	https://www.ncbi.nlm.nih.gov/gene/120112175	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	cytochrome P450 76T24	LOC110879566	https://www.ncbi.nlm.nih.gov/gene/110879566	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	cytochrome P450 93A3	LOC110942908	https://www.ncbi.nlm.nih.gov/gene/110942908	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	cytochrome P450 CYP72A219	LOC110895002	https://www.ncbi.nlm.nih.gov/gene/110895002	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	cytochrome P450 CYP749A22	LOC110918705	https://www.ncbi.nlm.nih.gov/gene/110918705	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	cytochrome P450 CYP82D47	LOC110923440	https://www.ncbi.nlm.nih.gov/gene/110923440	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	eupatolide synthase	LOC110929409	https://www.ncbi.nlm.nih.gov/gene/110929409	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	labd-13Z-ene-9,15,16-triol synthase, chloroplastic	LOC110941556	https://www.ncbi.nlm.nih.gov/gene/110941556	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	probable (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2	LOC110897567	https://www.ncbi.nlm.nih.gov/gene/110897567	--
HaCYP	CYP450	Helianthus annuus	Asteraceae	Yes	Sesquiterpene Lactones,Sesquiterpenes,Steroids,Polyphenols,Aromatics	--	LOC110941831	https://www.ncbi.nlm.nih.gov/gene/110941831	--
BrCYP	CYP450	Brassica rapa	Brassicaceae	Yes	Flavonoids,Phenolic Acids,Triterpenes,Polysaccharides	cytochrome P450 709B1	LOC103852728	https://www.ncbi.nlm.nih.gov/gene/103852728	--
BrCYP	CYP450	Brassica rapa	Brassicaceae	Yes	Flavonoids,Phenolic Acids,Triterpenes,Polysaccharides	cytochrome P450 71A14	LOC103874339	https://www.ncbi.nlm.nih.gov/gene/103874339	--
BrCYP	CYP450	Brassica rapa	Brassicaceae	Yes	Flavonoids,Phenolic Acids,Triterpenes,Polysaccharides	cytochrome P450 72A13	LOC103841893	https://www.ncbi.nlm.nih.gov/gene/103841893	--
BrCYP	CYP450	Brassica rapa	Brassicaceae	Yes	Flavonoids,Phenolic Acids,Triterpenes,Polysaccharides	cytochrome P450 81D11	LOC103854185	https://www.ncbi.nlm.nih.gov/gene/103854185	--
BrCYP18-3	CYP450	Brassica rapa	Brassicaceae	Yes	Flavonoids,Phenolic Acids,Triterpenes,Polysaccharides	peptidyl-prolyl cis-trans isomerase CYP18-3	LOC100777759	https://www.ncbi.nlm.nih.gov/gene/100777759	--
AtCYP1	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 1	AT4G38740	https://www.ncbi.nlm.nih.gov/gene/830029	Kosmacz M, Gorka M, Schmidt S, et al. Protein and metabolite composition of Arabidopsis stress granules. New Phytol. 2019;222(3):1420-1433. doi:10.1111/nph.15690
AtCYP3	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 3	AT2G16600	https://www.ncbi.nlm.nih.gov/gene/816161	Mair A, Xu SL, Branon TC, Ting AY, Bergmann DC. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Elife. 2019;8:e47864. doi:10.7554/eLife.47864
AtCYP3	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 3	AT2G16600	https://www.ncbi.nlm.nih.gov/gene/816161	Mair A, Xu SL, Branon TC, Ting AY, Bergmann DC. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Elife. 2019;8:e47864. doi:10.7554/eLife.47864
AtCYP4	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 4	LOC825376	https://www.ncbi.nlm.nih.gov/gene/825376	Liebthal M, Strüve M, Li X, et al. Redox-Dependent Conformational Dynamics of Decameric 2-Cysteine Peroxiredoxin and its Interaction with Cyclophilin 20-3. Plant Cell Physiol. 2016;57(7):1415-1425. doi:10.1093/pcp/pcw031
AtCYP4	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 4	LOC825376	https://www.ncbi.nlm.nih.gov/gene/825376	Liebthal M, Strüve M, Li X, et al. Redox-Dependent Conformational Dynamics of Decameric 2-Cysteine Peroxiredoxin and its Interaction with Cyclophilin 20-3. Plant Cell Physiol. 2016;57(7):1415-1425. doi:10.1093/pcp/pcw031
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	AT3G44970	https://www.ncbi.nlm.nih.gov/gene/823632	--
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	CYP71B30P	https://www.ncbi.nlm.nih.gov/gene/824496	--
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	CYP79A3P	https://www.ncbi.nlm.nih.gov/gene/833580	--
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	CYP716A1	https://www.ncbi.nlm.nih.gov/gene/833607	--
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	AT5G36130	https://www.ncbi.nlm.nih.gov/gene/833610	--
AtCYP	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	cytochrome P450	CYP708A3	https://www.ncbi.nlm.nih.gov/gene/844185	--
AtCYP1	CYP450	Arabidopsis thaliana	Brassicaceae	Yes	Indole-3-acetic Acid	rotamase CYP 1	AT4G38740	https://www.ncbi.nlm.nih.gov/gene/830029	Kosmacz M, Gorka M, Schmidt S, et al. Protein and metabolite composition of Arabidopsis stress granules. New Phytol. 2019;222(3):1420-1433. doi:10.1111/nph.15690
BnCYP	CYP450	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	cytochrome P450 72C1	LOC106414937	https://www.ncbi.nlm.nih.gov/gene/106414937	--
BnCYP	CYP450	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	cytochrome P450 98A8	LOC106405584	https://www.ncbi.nlm.nih.gov/gene/106405584	--
BnCYP	CYP450	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	peptidyl-prolyl cis-trans isomerase	LOC106347045	https://www.ncbi.nlm.nih.gov/gene/106347045	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 711A1	LOC119997666	https://www.ncbi.nlm.nih.gov/gene/119997666	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 714A1	LOC119996206	https://www.ncbi.nlm.nih.gov/gene/119996206	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 71D10	LOC119986046	https://www.ncbi.nlm.nih.gov/gene/119986046	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 734A1	LOC120009369	https://www.ncbi.nlm.nih.gov/gene/120009369	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 87A3	LOC119990223	https://www.ncbi.nlm.nih.gov/gene/119990223	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytochrome P450 CYP749A22	LOC120015502	https://www.ncbi.nlm.nih.gov/gene/120015502	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	cytokinin hydroxylase	LOC119989676	https://www.ncbi.nlm.nih.gov/gene/119989676	--
TwCYP	CYP450	Tripterygium wilfordii	Celastraceae	Yes	Triptolide,Triptolide A,Triptolide B,Triptolide B	--	LOC120005313	https://www.ncbi.nlm.nih.gov/gene/120005313	--
BvCYP76AD1	CYP450	Beta vulgaris	Chenopodiaceae	No	Anthocyanins,Tannins	--	HQ656023	https://www.ncbi.nlm.nih.gov/gene/?term=HQ656023	Hatlestad, G.J., Sunnadeniya, R.M., Akhavan, N.A., Gonzalez, A., Goldman, I.L., McGrath,J.M., Lloyd, A.M., 2012. The beet R locus encodes a new cytochrome P450 required for red betalain production. Nat. Genet. 44, 816–820.
GsCYP75A110	CYP450	Gloriosa superba	Colchicaceae	Yes	Colchicine	cytochrome P450	QLI49056.1	https://www.ncbi.nlm.nih.gov/protein/QLI49056.1	Bhambhani S,Kondhare KR,Giri AP. Diversity in Chemical Structures and Biological Properties of Plant Alkaloids. Molecules. 2021;26 (11):null. doi:10.3390/molecules26113374
GsCYP75A109	CYP450	Gloriosa superba	Colchicaceae	Yes	Colchicine	--	QLI49053.1	https://www.ncbi.nlm.nih.gov/protein/QLI49053.1	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11 (10):. doi:10.3390/antibiotics11101380
McCYP	CYP450	Momordica charantia	Cucurbitaceae	Yes	Bitter Gourd Extract,Peptide-P	peptidyl-prolyl cis-trans isomerase	LOC111007901	https://www.ncbi.nlm.nih.gov/gene/111007901	--
CsCYP72A219	CYP450	Cucumis sativus	Cucurbitaceae	Yes	Carbohydrates,Carotene,Niacin,Calcium,Phosphorus	cytochrome P450 CYP72A219	LOC101213974	https://www.ncbi.nlm.nih.gov/gene/101213974	--
RvCYP	CYP450	Rhododendron vialii	Ericaceae	Yes	Lignan	assisting alcohol dehydrogenase	LOC131301494	https://www.ncbi.nlm.nih.gov/gene/131301494	--
RcCYP	CYP450	Ricinus communis	Euphorbiaceae	Yes	Triacylglycerol,Castor Alkaloid	p-coumarate 3-hydroxylase	LOC8277408	https://www.ncbi.nlm.nih.gov/gene/8277408	--
GmCYP	CYP450	Glycine max	Papilionaceae	No	Calcium,Phosphorus	peptidyl-prolyl cis-trans isomerase 1	LOC100777759	https://www.ncbi.nlm.nih.gov/gene/100777759	--
LjCYP	CYP450	Lotus japonicus	Fabaceae	Yes	Corniculatusin	assisting alcohol dehydrogenase	LOC130747806	https://www.ncbi.nlm.nih.gov/gene/130747806	--
CaCYP	CYP450	Cicer arietinum	Fabaceae	Yes	Polysaccharides,Phospholipids,Phenols,Isoflavones	cytochrome P450 monooxygenase	LOC101501904	https://www.ncbi.nlm.nih.gov/gene/101501904	--
VaCYP	CYP450	Vigna angularis	Fabaceae	Yes	Triterpenoidsaponin	cytochrome P450 714C2	LOC108341189	https://www.ncbi.nlm.nih.gov/gene/108341189	--
MsCYP	CYP450	Magnolia sinica	Magnoliaceae	Yes	Phenols,Magnolia Alkaloids	assisting alcohol dehydrogenase	LOC131232841	https://www.ncbi.nlm.nih.gov/gene/131232841	--
GhCYP	CYP450	Gossypium hirsutum	Malvaceae	Yes	Cellulose	cytochrome P450 86A1	LOC107917892	https://www.ncbi.nlm.nih.gov/gene/107917892	--
VcCYP90B27	CYP450	Veratrum californicum	Melanthiaceae	Yes	Colchicine,β-Sitosterol	--	KJ869252	https://www.ncbi.nlm.nih.gov/nuccore/KJ869252	Augustin MM,Ruzicka DR,Shukla AK, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015;82 (6):991-1003. doi:10.1111/tpj.12871
VcCYP90G1	CYP450	Veratrum californicum	Melanthiaceae	Yes	Colchicine,β-Sitosterol	--	KJ869260.1	https://www.ncbi.nlm.nih.gov/nuccore/KJ869260.1	Augustin MM,Ruzicka DR,Shukla AK, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015;82 (6):991-1003. doi:10.1111/tpj.12871
VcCYP94N1	CYP450	Veratrum californicum	Melanthiaceae	Yes	Colchicine,β-Sitosterol	--	KJ869255.1	https://www.ncbi.nlm.nih.gov/nuccore/KJ869255.1	Augustin MM,Ruzicka DR,Shukla AK, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015;82 (6):991-1003. doi:10.1111/tpj.12871
EgCYP	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	--	LOC104417598	https://www.ncbi.nlm.nih.gov/gene/104417598	--
EgCYP	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cucurbitadienol 11-hydroxylase	LOC104417599	https://www.ncbi.nlm.nih.gov/gene/104417599	--
EgCYP71AP13	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450 71AP13	LOC104417541	https://www.ncbi.nlm.nih.gov/gene/104417541	--
EgCYP71D95	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450 71D95	LOC104417833	https://www.ncbi.nlm.nih.gov/gene/104417833	--
EgCYP81E8-like	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450 81E8-like	LOC104420374	https://www.ncbi.nlm.nih.gov/gene/104420374	--
EgCYP93A3-like	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450 93A3-like	LOC104420553	https://www.ncbi.nlm.nih.gov/gene/104420553	--
EgCYP71D312	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450 CYP71D312	LOC104417836	https://www.ncbi.nlm.nih.gov/gene/104417836	--
EgCYP	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	premnaspirodiene oxygenase	LOC104420602	https://www.ncbi.nlm.nih.gov/gene/104420602	--
EgCYP	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	tyrosine N-monooxygenase	LOC104417845	https://www.ncbi.nlm.nih.gov/gene/104417845	--
EgCYP	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	valine N-monooxygenase 1	LOC104420178	https://www.ncbi.nlm.nih.gov/gene/104420178	--
EgCYP714C2	CYP450	Eucalyptus grandis	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	cytochrome P450	LOC104421742	https://www.ncbi.nlm.nih.gov/gene/104421742	--
NnCYP719A22	CYP450	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	methylenedioxy bridge synthase	OP795716	https://www.ncbi.nlm.nih.gov/gene/?term=OP795716	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
NnCYP80Q1	CYP450	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	proaporphine synthase	OP795717	https://www.ncbi.nlm.nih.gov/gene/?term=OP795717	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
NnCYP80Q2	CYP450	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	bisbenzylisoquinoline synthase	OP795718	https://www.ncbi.nlm.nih.gov/gene/?term=OP795718	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
EcCYP82B1	CYP450	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	protopine 6-hydroxylase	BAK20464.1	https://www.ncbi.nlm.nih.gov/protein/BAK20464.1	Hori K,Yamada Y,Purwanto R, et al. Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence. Plant Cell Physiol. 2018;59 (2):222-233. doi:10.1093/pcp/pcx210
EcCYP82N5	CYP450	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	(S)-N-methylcoclaurine 3'-hydroxylase	AAC39454.1	https://www.ncbi.nlm.nih.gov/protein/AAC39454.1	Hori K,Yamada Y,Purwanto R, et al. Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence. Plant Cell Physiol. 2018;59 (2):222-233. doi:10.1093/pcp/pcx210
EcCYP80B1	CYP450	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	(S)-N-methylcoclaurine 3'-hydroxylase	AF014801	https://www.ncbi.nlm.nih.gov/nuccore/AF014801	Pauli HH,Kutchan TM. Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3'-hydroxylase (CYP80B1), a new methyl jasmonate-inducible cytochrome P-450-dependent mono-oxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J. 1998;13 (6):793-801. doi:10.1046/j.1365-313x.1998.00085.x
EcCYP82N2v2	CYP450	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	protopine 6-hydroxylase	AB598834	https://www.ncbi.nlm.nih.gov/nuccore/AB598834	Takemura T,Ikezawa N,Iwasa K, et al. Molecular cloning and characterization of a cytochrome P450 in sanguinarine biosynthesis from Eschscholzia californica cells. Phytochemistry. 2013;91:100-8. doi:10.1016/j.phytochem.2012.02.013
PsCYP82Y1	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P451	JQ659005	https://www.ncbi.nlm.nih.gov/nuccore/JQ659005	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505099
PsCYP82X1	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P450	JQ659002	https://www.ncbi.nlm.nih.gov/nuccore/JQ659002	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505100
PsCYP82X2	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P450	JQ659004	https://www.ncbi.nlm.nih.gov/nuccore/JQ659004	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505101
CjCYP82R1	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P450	BAF98472	https://www.ncbi.nlm.nih.gov/protein/BAF98472	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505102
PsCYP82N3	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	protopine 6-hydroxylase	KC154002	https://www.ncbi.nlm.nih.gov/nuccore/KC154002	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505103
PsCYP719A21	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P450	JQ659003	https://www.ncbi.nlm.nih.gov/nuccore/JQ659003	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505105
PsCYP719B1	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	salutaridine synthase	ABR14720	https://www.ncbi.nlm.nih.gov/protein/ABR14720	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505106
PsCYP719A25	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cheilanthifoline synthase	GU325749	https://www.ncbi.nlm.nih.gov/nuccore/GU325749	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505107
CjCYP80G2	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	corytuberine synthase	AB288053	https://www.ncbi.nlm.nih.gov/nuccore/AB288053	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505110
AtCYP82C2	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	Indole-3-carbonyl nitrile 4-hydroxylase	O49394	https://www.ncbi.nlm.nih.gov/protein/O49394	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505111
NtCYP82E4v1	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P450 monooxygenase	DQ131886	https://www.ncbi.nlm.nih.gov/nuccore/DQ131886	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505112
VvCYP82C4	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	cytochrome P452	XP_02284810	https://www.ncbi.nlm.nih.gov/nuccore/?term=XP_02284810	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505114
GmCYP82G4	CYP450	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	xanthotoxin 5-hydroxylase	XP_003523888	https://www.ncbi.nlm.nih.gov/protein/XP_003523888	Dang TT,Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem. 2014;289 (4):2013-26. doi:10.1074/jbc.M113.505115
CjCYP719A1	CYP450	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	methylenedioxy bridge-forming enzyme	AB026122.1	https://www.ncbi.nlm.nih.gov/gene/?term=AB026122.1	Liu Y,Wang B,Shu S, et al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nat Commun. 2021;12 (1):3276. doi:10.1038/s41467-021-23611-0
CjCYP719A18	CYP450	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	protoberberine-type alkaloids	ANY58145.1	https://www.ncbi.nlm.nih.gov/gene/?term=ANY58145.1	Liu Y,Wang B,Shu S, et al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nat Commun. 2021;12 (1):3276. doi:10.1038/s41467-021-23611-1
CjCYP719A19	CYP450	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	protoberberine-type alkaloids	ANY58146.1	https://www.ncbi.nlm.nih.gov/gene/?term=ANY58146.1	Liu Y,Wang B,Shu S, et al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nat Commun. 2021;12 (1):3276. doi:10.1038/s41467-021-23611-2
EcCYP719A2	CYP450	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	protoberberine-type alkaloids	AB126257.1	https://www.ncbi.nlm.nih.gov/gene/?term=AB126257.1	Liu Y,Wang B,Shu S, et al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nat Commun. 2021;12 (1):3276. doi:10.1038/s41467-021-23611-3
EcCYP719A5	CYP450	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	protoberberine-type alkaloids	AB434654.1	https://www.ncbi.nlm.nih.gov/gene/?term=AB434654.1	Liu Y,Wang B,Shu S, et al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nat Commun. 2021;12 (1):3276. doi:10.1038/s41467-021-23611-4
ZjCYP	CYP450	Ziziphus jujuba	Rhamnaceae	Yes	Phenols,Flavonoids,Polysaccharides,Vitamin C,Pentacyclic Triterpenoids,Saponins,Lauric Acid,β-Carotene	assisting alcohol dehydrogenase	LOC107414727	https://www.ncbi.nlm.nih.gov/gene/107414727	--
ZjCYP	CYP450	Ziziphus jujuba	Rhamnaceae	Yes	Phenols,Flavonoids,Polysaccharides,Vitamin C,Pentacyclic Triterpenoids,Saponins,Lauric Acid,β-Carotene	peptidyl-prolyl cis-trans isomerase CYP19-3	LOC107412176	https://www.ncbi.nlm.nih.gov/gene/107412176	--
RcCYP	CYP450	Rosa chinensis	Rosaceae	Yes	Flavonoids,Phenolic Acids,Pentacyclic Triterpenes,Steroids	labd-13Z-ene-9,15,16-triol synthase	LOC112178526	https://www.ncbi.nlm.nih.gov/gene/112178526	--
RcCYP	CYP450	Rosa chinensis	Rosaceae	Yes	Flavonoids,Phenolic Acids,Pentacyclic Triterpenes,Steroids	protein DETOXIFICATION 45	LOC112172234	https://www.ncbi.nlm.nih.gov/gene/112172234	--
PdCYP	CYP450	Prunus dulcis	Rosaceae	Yes	Sterols,Methylsterols,Triterpenols,Hydrocarbons	alpha-humulene 10-hydroxylase	LOC117618671	https://www.ncbi.nlm.nih.gov/gene/117618671	--
PdCYP	CYP450	Prunus dulcis	Rosaceae	Yes	Sterols,Methylsterols,Triterpenols,Hydrocarbons	cytochrome P450 CYP749A22	LOC117637521	https://www.ncbi.nlm.nih.gov/gene/117637521	--
CsCYP	CYP450	Citrus sinensis	Rutaceae	Yes	Decanal,Citral,Limonene,Octanol	assisting alcohol dehydrogenase	LOC102623660	https://www.ncbi.nlm.nih.gov/gene/102623660	--
CsCYP	CYP450	Citrus sinensis	Rutaceae	Yes	Decanal,Citral,Limonene,Octanol	assisting alcohol dehydrogenase	LOC115716320	https://www.ncbi.nlm.nih.gov/gene/115716320	--
CsCYP	CYP450	Citrus sinensis	Rutaceae	Yes	Decanal,Citral,Limonene,Octanol	peptidyl-prolyl cis-trans isomerase	LOC101501904	https://www.ncbi.nlm.nih.gov/gene/101501904	--
CaCYP	CYP450	Capsicum annuum	Solanaceae	Yes	Capsaicin	cysteine proteinase 3	LOC107877862	https://www.ncbi.nlm.nih.gov/gene/107877862	--
StCYP	CYP450	Solanum tuberosum	Solanaceae	Yes	Carbohydrates,Cellulose	low-temperature-induced cysteine proteinase	LOC102582822	https://www.ncbi.nlm.nih.gov/gene/102582822	--
SlCYP	CYP450	Solanum lycopersicum	Solanaceae	Yes	Carotenoids	--	LOC100736432	https://www.ncbi.nlm.nih.gov/gene/100736432	--
SlCYP	CYP450	Solanum lycopersicum	Solanaceae	Yes	Carotenoids	Cyp-3 cysteine proteinase	LOC101252505	https://www.ncbi.nlm.nih.gov/gene/101252505	--
AbCYP82M3	CYP450	Atropa belladonna	Solanaceae	Yes	Hyoscyamine,Atropine,Scopolamine,Belladonin	tropinone synthase	MH292964	https://www.ncbi.nlm.nih.gov/nuccore/MH292964.1/	Bedewitz MA,Jones AD,D'Auria JC, et al. Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization. Nat Commun. 2018;9 (1):5281. doi:10.1038/s41467-018-07671-3
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	(S)-N-methylcoclaurine 3'-hydroxylase isozyme 2	LOC104102595	https://www.ncbi.nlm.nih.gov/gene/104102595	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	3,9-dihydroxypterocarpan 6A-monooxygenase-like	LOC104096160	https://www.ncbi.nlm.nih.gov/gene/104096160	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	alkane hydroxylase MAH1	LOC104100153	https://www.ncbi.nlm.nih.gov/gene/104100153	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	cytochrome P450 714B1-like	LOC104113159	https://www.ncbi.nlm.nih.gov/gene/104113159	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	cytochrome P450 714C2-like	LOC104121060	https://www.ncbi.nlm.nih.gov/gene/104121060	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	cytochrome P450 734A1-like	LOC104085859	https://www.ncbi.nlm.nih.gov/gene/104085859	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	cytochrome P450 89A2-like	LOC104118408	https://www.ncbi.nlm.nih.gov/gene/104118408	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	cytochrome P450 93A3-like	LOC104097413	https://www.ncbi.nlm.nih.gov/gene/104097413	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	geraniol 8-hydroxylase-like	LOC104120481	https://www.ncbi.nlm.nih.gov/gene/104120481	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	isoleucine N-monooxygenase	LOC104095765	https://www.ncbi.nlm.nih.gov/gene/104095765	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	isoleucine N-monooxygenase 1-like	LOC104097091	https://www.ncbi.nlm.nih.gov/gene/104097091	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	premnaspirodiene oxygenase	LOC104103514	https://www.ncbi.nlm.nih.gov/gene/104103514	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	premnaspirodiene oxygenase-like	LOC104103395	https://www.ncbi.nlm.nih.gov/gene/104103395	--
NtCYP	CYP450	Nicotiana tomentosiformis	Solanaceae	Yes	L-nicotine,Quinine,Dehydrotoxine,Nicotine	--	LOC104093267	https://www.ncbi.nlm.nih.gov/gene/104093267	--
LrOMT	OMT	Lycoris radiata	Amaryllidaceae	Yes	Lycine,Homolycorine,Pseudolycorine,Alicin,Demethyl Allicin,Demethyl Homolycorine,Allicin,Narcissus,Allicin	O-methyltransferase	MK805029.1	https://www.ncbi.nlm.nih.gov/nuccore/MK805029.1	Li W, Qiao C, Pang J, Zhang G, Luo Y. The versatile O-methyltransferase LrOMT catalyzes multiple O-methylation reactions in amaryllidaceae alkaloids biosynthesis. Int J Biol Macromol. 2019;141:680-692. doi:10.1016/j.ijbiomac.2019.09.011
RsOMT	OMT	Rauvolfia serpentina	Apocynaceae	Yes	γ-Linoleic Acid,Fatty Acids,Carotenoids	caffeic acid O-methyltransferase	KX687825.1	https://www.ncbi.nlm.nih.gov/nuccore/KX687825.1	Wiens B, De Luca V. Molecular and biochemical characterization of a benzenoid/phenylpropanoid meta/para-O-methyltransferase from Rauwolfia serpentina roots. Phytochemistry. 2016;132:5-15. doi:10.1016/j.phytochem.2016.10.004
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	CM060867.1	https://www.ncbi.nlm.nih.gov/nuccore/CM060867.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	CM060868.1	https://www.ncbi.nlm.nih.gov/nuccore/CM060868.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	CM060877.1	https://www.ncbi.nlm.nih.gov/nuccore/CM060877.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	CM060879.1	https://www.ncbi.nlm.nih.gov/nuccore/CM060879.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	JAUJYO000000000.1	https://www.ncbi.nlm.nih.gov/nuccore/JAUJYO000000000.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	JAUJYO010000010.1	https://www.ncbi.nlm.nih.gov/nuccore/JAUJYO010000010.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	JAUJYO010000011.1	https://www.ncbi.nlm.nih.gov/nuccore/JAUJYO010000011.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	JAUJYO010000020.1	https://www.ncbi.nlm.nih.gov/nuccore/JAUJYO010000020.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
ACOMT	OMT	Acorus calamus	Araceae	Yes	β- Asarone,α-Asarum Ether	--	JAUJYO010000022.1	https://www.ncbi.nlm.nih.gov/nuccore/JAUJYO010000022.1	Givnish TJ, et al. Monocot plastid phylogenomics, timeline, net rates of species diversification, the power of multi-gene analyses, and a functional model for the origin of monocots. Am. J. Bot. 2018;105:1888–1910.
EgOMT	OMT	Elaeis guineensis	Arecaceae	Yes	Carotenoids	trans-resveratrol di-O-methyltransferase	JN003483.1	https://www.ncbi.nlm.nih.gov/nuccore/JN003483.1	--
N7OMT	OMT	Berberis koreana	Berberidaceae	Yes	Berberine,Oxyacanthine,Jatrorrhizine,Magnoflorine,Berbamine	--	--	--	Roy NS,Choi IY,Um T, et al. Gene Expression and Isoform Identification of PacBio Full-Length cDNA Sequences for Berberine Biosynthesis in Berberis koreana. Plants (Basel). 2021;10 (7):null. doi:10.3390/plants10071314
SOMT	OMT	Berberis koreana	Berberidaceae	Yes	Berberine,Oxyacanthine,Jatrorrhizine,Magnoflorine,Berbamine	--	--	--	Roy NS,Choi IY,Um T, et al. Gene Expression and Isoform Identification of PacBio Full-Length cDNA Sequences for Berberine Biosynthesis in Berberis koreana. Plants (Basel). 2021;10 (7):null. doi:10.3390/plants10071315
HNMC4’OMT	OMT	Sinopodophyllum hexandrum	Berberidaceae	Yes	Cardiac Glycosides,Steroidal Saponins	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase	KJ786960	https://www.ncbi.nlm.nih.gov/nuccore/KJ786960	Yu X, Liu Z, Sun X. Single-cell and spatial multi-omics in the plant sciences: Technical advances, applications, and perspectives. Plant Commun. 2023;4(3):100508. doi:10.1016/j.xplc.2022.100508
ShCCoA-OMT	OMT	Sinopodophyllum hexandrum	Berberidaceae	Yes	Cardiac Glycosides,Steroidal Saponins	caffeoyl CoA O-methyltransferase	MW531750.1	https://www.ncbi.nlm.nih.gov/nuccore/MW531750.1	--
ShOMT	OMT	Sinopodophyllum hexandrum	Berberidaceae	Yes	Cardiac Glycosides,Steroidal Saponins	catechol O-methyltransferase	FK934374.1	https://www.ncbi.nlm.nih.gov/nuccore/FK934374.1	--
BnOMT	OMT	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	O-methyltransferase	JX258816.1	https://www.ncbi.nlm.nih.gov/nuccore/JX258816.1	--
BnOMT	OMT	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	O-methyltransferase	JX258815.1	https://www.ncbi.nlm.nih.gov/nuccore/JX258815.1	--
BnOMT	OMT	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	O-methyltransferase	JX258814.1	https://www.ncbi.nlm.nih.gov/nuccore/JX258814.1	--
BnOMT	OMT	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	O-methyltransferase	KJ914580.1	https://www.ncbi.nlm.nih.gov/nuccore/KJ914580.1	--
BnOMT	OMT	Brassica napus	Brassicaceae	No	Isothiocyanate,Indole Compounds,Carotene	O-methyltransferase	KJ914579.1	https://www.ncbi.nlm.nih.gov/nuccore/KJ914579.1	--
BjSadmt	OMT	Brassica juncea	Brassicaceae	Yes	Thioglucoside	S-adenosylmethionine-dependent methyltransferase	HM627211.1	https://www.ncbi.nlm.nih.gov/nuccore/HM627211.1	--
GsOMT1	OMT	Gloriosa superba	Colchicaceae	Yes	Colchicine	O-methyltransferase	MT512039	https://www.ncbi.nlm.nih.gov/nuccore/MT512039)	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11(10):1380. doi:10.3390/antibiotics11101380
GsNMT1	OMT	Gloriosa superba	Colchicaceae	Yes	Colchicine	--	--	--	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11(10):1380. doi:10.3390/antibiotics11101380
GsOMT2	OMT	Gloriosa superba	Colchicaceae	Yes	Colchicine	O-methyltransferase	MT512043	https://www.ncbi.nlm.nih.gov/nuccore/MT512043	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11(10):1380. doi:10.3390/antibiotics11101380
GsOMT3	OMT	Gloriosa superba	Colchicaceae	Yes	Colchicine	O-methyltransferase	MT512044	https://www.ncbi.nlm.nih.gov/nuccore/MT512044	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11(10):1380. doi:10.3390/antibiotics11101380
GsOMT4	OMT	Gloriosa superba	Colchicaceae	Yes	Colchicine	O-methyltransferase	MT512046	https://www.ncbi.nlm.nih.gov/nuccore/MT512046	Huang W,Wang Y,Tian W, et al. Biosynthesis Investigations of Terpenoid, Alkaloid, and Flavonoid Antimicrobial Agents Derived from Medicinal Plants. Antibiotics (Basel). 2022;11(10):1380. doi:10.3390/antibiotics11101380
VcOMT	OMT	Vaccinium corymbosum	Ericaceae	Yes	Anthocyanin	O-methyltransferase	KJ830748.1	https://www.ncbi.nlm.nih.gov/nuccore/KJ830748.1	--
NtPMT	OMT	Caragana korshinskii kom	Fabaceae	Yes	Anthocyanidin,Hemicellulose	Putrescine N-Methyltransferase	DD093782.1	https://www.ncbi.nlm.nih.gov/nuccore/DD093782.1	Xia K,Liu X,Zhang Q, et al. Promoting scopolamine biosynthesis in transgenic Atropa belladonna plants with pmt and h6h overexpression under field conditions. Plant Physiol Biochem. 2016;106:46-53. doi:10.1016/j.plaphy.2016.04.034
Ps2OMT	OMT	Pisum sativum	Papilionaceae	Yes	Carotenoids	plastidic 2-oxoglutarate	FN297817.1	https://www.ncbi.nlm.nih.gov/nuccore/FN297817.1	Riebeseel E, Häusler RE, Radchuk R, et al. The 2-oxoglutarate/malate translocator mediates amino acid and storage protein biosynthesis in pea embryos. Plant J. 2010;61(2):350-363. doi:10.1111/j.1365-313X.2009.04058.x
LuOMT	OMT	Lotus uliginosus	Fabaceae	Yes	Corniculatusin,Corniculatusin-3-O-β-D-galactoside	O-methyltransferase	EH380094.1	https://www.ncbi.nlm.nih.gov/nuccore/EH380094.1	--
MtOMT1	OMT	Medicago truncatula	Fabaceae	Yes	Coumarins,Polysaccharides,Saponins	--	BV165455.1	https://www.ncbi.nlm.nih.gov/nuccore/BV165455.1	Choi HK, Luckow MA, Doyle J, Cook DR. Development of nuclear gene-derived molecular markers linked to legume genetic maps. Mol Genet Genomics. 2006;276(1):56-70. doi:10.1007/s00438-006-0118-8
MtOMT2	OMT	Medicago truncatula	Fabaceae	Yes	Coumarins,Polysaccharides,Saponins	--	BV165456.1	https://www.ncbi.nlm.nih.gov/nuccore/BV165456.1	Choi HK, Luckow MA, Doyle J, Cook DR. Development of nuclear gene-derived molecular markers linked to legume genetic maps. Mol Genet Genomics. 2006;276(1):56-70. doi:10.1007/s00438-006-0118-8
VaOMT	OMT	Vigna angularis	Fabaceae	Yes	Triterpenoidsaponin	--	CM003374.1	https://www.ncbi.nlm.nih.gov/nuccore/CM003374.1	--
TaOMT1	OMT	Triticum aestivum	Gramineae	Yes	Albumin,Globulin,Gliadin,Glutenin	1 caffeoyl-CoA O-methyltransferase 1	MG979066.1	https://www.ncbi.nlm.nih.gov/nuccore/MG979066.1	Li X, Qian X, Lǚ X, et al. Upregulated structural and regulatory genes involved in anthocyanin biosynthesis for coloration of purple grains during the middle and late grain-filling stages. Plant Physiol Biochem. 2018;130:235-247. doi:10.1016/j.plaphy.2018.07.011
TaOMT	OMT	Triticum aestivum	Gramineae	Yes	Albumin,Globulin,Gliadin,Glutenin	O-methyltransferase	EC907558.1	https://www.ncbi.nlm.nih.gov/nuccore/EC907558.1	--
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP014965.1	https://www.ncbi.nlm.nih.gov/nuccore/AP014965.1	Kawahara Y, de la Bastide M, Hamilton JP, et al. Improvement of the Oryza sativa Nipponbare reference genome using next generation sequence and optical map data. Rice (N Y). 2013;6(1):4. doi:10.1186/1939-8433-6-4
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP014961.1	https://www.ncbi.nlm.nih.gov/nuccore/AP014961.1	Kawahara Y, de la Bastide M, Hamilton JP, et al. Improvement of the Oryza sativa Nipponbare reference genome using next generation sequence and optical map data. Rice (N Y). 2013;6(1):4. doi:10.1186/1939-8433-6-4
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP008212.2	https://www.ncbi.nlm.nih.gov/nuccore/AP008212.2	Ohyanagi H, Tanaka T, Sakai H, et al. The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res. 2006;34(Database issue):D741-D744. doi:10.1093/nar/gkj094
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP008218.2	https://www.ncbi.nlm.nih.gov/nuccore/AP008218.2	Ohyanagi H, Tanaka T, Sakai H, et al. The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res. 2006;34(Database issue):D741-D744. doi:10.1093/nar/gkj094
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP008215.2	https://www.ncbi.nlm.nih.gov/nuccore/AP008215.2	Ohyanagi H, Tanaka T, Sakai H, et al. The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res. 2006;34(Database issue):D741-D744. doi:10.1093/nar/gkj094
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP008211.2	https://www.ncbi.nlm.nih.gov/nuccore/AP008211.2	Ohyanagi H, Tanaka T, Sakai H, et al. The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res. 2006;34(Database issue):D741-D744. doi:10.1093/nar/gkj094
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AP008216.2	https://www.ncbi.nlm.nih.gov/nuccore/AP008216.2	Ohyanagi H, Tanaka T, Sakai H, et al. The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res. 2006;34(Database issue):D741-D744. doi:10.1093/nar/gkj094
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	EU882982.1	https://www.ncbi.nlm.nih.gov/nuccore/AK072740.1	Rice Full-Length cDNA Consortium; National Institute of Agrobiological Sciences Rice Full-Length cDNA Project Team, Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science. 2003;301(5631):376-379. doi:10.1126/science.1081288
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AK069721.1	https://www.ncbi.nlm.nih.gov/nuccore/AK069721.1	Rice Full-Length cDNA Consortium; National Institute of Agrobiological Sciences Rice Full-Length cDNA Project Team, Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science. 2003;301(5631):376-379. doi:10.1126/science.1081288
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AK069308.1	https://www.ncbi.nlm.nih.gov/nuccore/AK069308.1	Rice Full-Length cDNA Consortium; National Institute of Agrobiological Sciences Rice Full-Length cDNA Project Team, Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science. 2003;301(5631):376-379. doi:10.1126/science.1081288
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	--	AK068905.1	https://www.ncbi.nlm.nih.gov/nuccore/AK068905.1	Rice Full-Length cDNA Consortium; National Institute of Agrobiological Sciences Rice Full-Length cDNA Project Team, Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science. 2003;301(5631):376-379. doi:10.1126/science.1081288
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	O-methyltransferase	CB096268.1	https://www.ncbi.nlm.nih.gov/nuccore/CB096268.1	--
OsOMT	OMT	Oryza sativa	Gramineae	Yes	Anthocyanidin,Hemicellulose	O-methyltransferase	CA764922.1	https://www.ncbi.nlm.nih.gov/nuccore/CA764922.1	--
Id6OMT	OMT	Iris dichotoma	Iridaceae	Yes	Volatile Oils	O-methyltransferase	MW525205.1	https://www.ncbi.nlm.nih.gov/nuccore/MW525205.1	--
MXvOdOMT	OMT	Medicago sativa subsp. X varia	Fabaceae	Yes	Alfalfa Polysaccharides,Alfalfa Saponins	O-diphenol-O-methyl transferase	AJ248322.1	https://www.ncbi.nlm.nih.gov/nuccore/AJ248322.1	Jiménez-Zurdo JI, Frugier F, Crespi MD, Kondorosi A. Expression profiles of 22 novel molecular markers for organogenetic pathways acting in alfalfa nodule development. Mol Plant Microbe Interact. 2000;13(1):96-106. doi:10.1094/MPMI.2000.13.1.96
GaOMT	OMT	Genlisea aurea	Lentibulariaceae	No	γ-Linoleic Acid,Fatty Acids,Carotenoids	--	KE535343.1	https://www.ncbi.nlm.nih.gov/nuccore/KE535343.1	Leushkin EV, Sutormin RA, Nabieva ER, Penin AA, Kondrashov AS, Logacheva MD. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics. 2013;14:476. doi:10.1186/1471-2164-14-476
GaOMT	OMT	Genlisea aurea	Lentibulariaceae	No	γ-Linoleic Acid,Fatty Acids,Carotenoids	--	KE537233.1	https://www.ncbi.nlm.nih.gov/nuccore/KE537233.1	Leushkin EV, Sutormin RA, Nabieva ER, Penin AA, Kondrashov AS, Logacheva MD. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics. 2013;14:476. doi:10.1186/1471-2164-14-476
GaOMT	OMT	Genlisea aurea	Lentibulariaceae	No	γ-Linoleic Acid,Fatty Acids,Carotenoids	--	AUSU01008715.1	https://www.ncbi.nlm.nih.gov/nuccore/AUSU01008715.1	Leushkin EV, Sutormin RA, Nabieva ER, Penin AA, Kondrashov AS, Logacheva MD. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics. 2013;14:476. doi:10.1186/1471-2164-14-476
GaOMT	OMT	Genlisea aurea	Lentibulariaceae	No	γ-Linoleic Acid,Fatty Acids,Carotenoids	--	AUSU01010609.1	https://www.ncbi.nlm.nih.gov/nuccore/AUSU01010609.1	Leushkin EV, Sutormin RA, Nabieva ER, Penin AA, Kondrashov AS, Logacheva MD. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics. 2013;14:476. doi:10.1186/1471-2164-14-476
LtOMT	OMT	Linum tenue	Linaceae	Yes	Tocopherol,Lignans,Cyanide	--	CAMGYJ010000004.1	https://www.ncbi.nlm.nih.gov/nuccore/CAMGYJ010000004.1	--
GaOMT	OMT	Gossypium arboreum	Malvaceae	Yes	Palmitic Acid	--	KN399258.1	https://www.ncbi.nlm.nih.gov/nuccore/KN399258.1	--
GaOMT	OMT	Gossypium arboreum	Malvaceae	Yes	Palmitic Acid	--	KN400214.1	https://www.ncbi.nlm.nih.gov/nuccore/KN400214.1	--
GaOMT	OMT	Gossypium anomalum	Malvaceae	Yes	Polyester	--	CM033491.1	https://www.ncbi.nlm.nih.gov/nuccore/CM033491.1	Grover CE, Yuan D, Arick MA, et al. The Gossypium anomalum genome as a resource for cotton improvement and evolutionary analysis of hybrid incompatibility. G3 (Bethesda). 2021;11(11):jkab319. doi:10.1093/g3journal/jkab319
GaOMT	OMT	Gossypium anomalum	Malvaceae	Yes	Polyester	--	JAHUZN010000008.1	https://www.ncbi.nlm.nih.gov/nuccore/JAHUZN010000008.1	Grover CE, Yuan D, Arick MA, et al. The Gossypium anomalum genome as a resource for cotton improvement and evolutionary analysis of hybrid incompatibility. G3 (Bethesda). 2021;11(11):jkab319. doi:10.1093/g3journal/jkab319
GaOMT	OMT	Gossypium anomalum	Malvaceae	Yes	Polyester	--	CM033495.1	https://www.ncbi.nlm.nih.gov/nuccore/CM033495.1	Grover CE, Yuan D, Arick MA, et al. The Gossypium anomalum genome as a resource for cotton improvement and evolutionary analysis of hybrid incompatibility. G3 (Bethesda). 2021;11(11):jkab319. doi:10.1093/g3journal/jkab319
GaOMT	OMT	Gossypium anomalum	Malvaceae	Yes	Polyester	--	JAHUZN010000012.1	https://www.ncbi.nlm.nih.gov/nuccore/JAHUZN010000012.1	Grover CE, Yuan D, Arick MA, et al. The Gossypium anomalum genome as a resource for cotton improvement and evolutionary analysis of hybrid incompatibility. G3 (Bethesda). 2021;11(11):jkab319. doi:10.1093/g3journal/jkab319
MaMT1	OMT	Morus alba	Moraceae	Yes	Flavonoids,Phenols,Quinones,Triterpenes,Coumarins,Polyhydroxyalkaloids	serine hydroxymethyltransferase	OM140666	https://www.ncbi.nlm.nih.gov/nuccore/OM140666	Wan J,Liao Y,Liu J, et al. Screening, cloning and functional characterization of key methyltransferase genes involved in the methylation step of 1-deoxynojirimycin alkaloids biosynthesis in mulberry leaves. Planta. 2022;255 (6):121. doi:10.1007/s00425-022-03901-7
MaOMT	OMT	Morus alba	Moraceae	Yes	Flavonoids,Phenols,Quinones,Triterpenes,Coumarins,Polyhydroxyalkaloids	--	MN937270.1	https://www.ncbi.nlm.nih.gov/nuccore/MN937270.1	--
MaOMT	OMT	Morus alba	Moraceae	Yes	Flavonoids,Phenols,Quinones,Triterpenes,Coumarins,Polyhydroxyalkaloids	--	MN937269.1	https://www.ncbi.nlm.nih.gov/nuccore/MN937269.1	--
MaOMT	OMT	Morus alba	Moraceae	Yes	Flavonoids,Phenols,Quinones,Triterpenes,Coumarins,Polyhydroxyalkaloids	--	MN937268.1	https://www.ncbi.nlm.nih.gov/nuccore/MN937268.1	--
MaOMT	OMT	Morus alba	Moraceae	Yes	Flavonoids,Phenols,Quinones,Triterpenes,Coumarins,Polyhydroxyalkaloids	--	MN937267.1	https://www.ncbi.nlm.nih.gov/nuccore/MN937267.1	--
EgOMT	OMT	Eucalyptus gunnii	Myrtaceae	Yes	Eucalyptus Oil,Organic Acids,Tannins	O-Methyltransferase	X74814.1	https://www.ncbi.nlm.nih.gov/nuccore/X74814.1	Poeydomenge O, Boudet AM, Grima-Pettenati J. A cDNA encoding S-adenosyl-L-methionine:caffeic acid 3-O-methyltransferase from Eucalyptus. Plant Physiol. 1994;105(2):749-750. doi:10.1104/pp.105.2.749
NnOMT5	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	7-O-methyltransferase	OP795722	https://www.ncbi.nlm.nih.gov/nuccore/OP795722	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
NnOMT7	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	7-O-methyltransferase	OP795724	https://www.ncbi.nlm.nih.gov/nuccore/OP795724	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
NnOMT1	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	--	OP795721	https://www.ncbi.nlm.nih.gov/nuccore/OP795721	Menéndez-Perdomo IM,Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13 (1):2955. doi:10.1038/s41598-023-29415-0
NnOMT1	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	6-O-methyltransferase	XM_010245752	https://www.ncbi.nlm.nih.gov/nuccore/XM_010245752	Menéndez-Perdomo IM,Facchini PJ. Isolation and characterization of two O -methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in sacred lotus ( Nelumbo nucifera ). J Biol Chem. 2020;295 (6):1598-1612. doi:10.1074/jbc.RA119.011547
NnOMT5	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	6-O-methyltransferase	XM_010277761	https://www.ncbi.nlm.nih.gov/nuccore/XM_010277761	Menéndez-Perdomo IM,Facchini PJ. Isolation and characterization of two O -methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in sacred lotus ( Nelumbo nucifera ). J Biol Chem. 2020;295 (6):1598-1612. doi:10.1074/jbc.RA119.011548
NnCNMT	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	--	--	--	Pyne ME,Gold ND,Martin VJJ. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera). Metab Eng. 2023;77:162-173. doi:10.1016/j.ymben.2023.03.010
Nn6OMT	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	--	--	--	Pyne ME,Gold ND,Martin VJJ. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera). Metab Eng. 2023;77:162-173. doi:10.1016/j.ymben.2023.03.010
NnNCS	OMT	Nelumbo nucifera	Nymphaeaceae	Yes	Roemerine	--	--	--	Pyne ME,Gold ND,Martin VJJ. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera). Metab Eng. 2023;77:162-173. doi:10.1016/j.ymben.2023.03.010
DoOMT	OMT	Dendrobium officinale	Orchidaceae	Yes	Dendrobine	caffeoyl CoA O-methyltransferase	KF876839.1	https://www.ncbi.nlm.nih.gov/nuccore/KF876839.1	Gang Z, Ben-Xiang HU , Da-Wei Z, et al. Isolation and expression analysis of caffeoyl CoA O-methyltransferase gene in Dendrobium officinale[J]. Chinese Traditional and Herbal Drugs. 2014;45(8):1143-1149. doi:10.7501/j.issn.0253-2670.2014.08.019.
GeCCoA-OMT	OMT	Gastrodia elata	Orchidaceae	Yes	Phenylacetic Acid Compounds,Terpenoids	--	MW041608.1	https://www.ncbi.nlm.nih.gov/nuccore/MW041608.1	--
GflOMT1	OMT	Glaucium flavum	Papaveraceae	Yes	Blood Root Alkaloids	O-methyltransferase	KP176693	https://www.ncbi.nlm.nih.gov/nuccore/KP176693	Chang L, Hagel JM, Facchini PJ. Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum. Plant Physiol. 2015;169 (2):1127-40. doi:10.1104/pp.15.01240
GflOMT2	OMT	Glaucium flavum	Papaveraceae	Yes	Blood Root Alkaloids	O-methyltransferase	KP176694	https://www.ncbi.nlm.nih.gov/nuccore/KP176694	Chang L, Hagel JM, Facchini PJ. Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum. Plant Physiol. 2015;169 (2):1127-40. doi:10.1104/pp.15.01241
GflOMT6	OMT	Glaucium flavum	Papaveraceae	Yes	Blood Root Alkaloids	O-methyltransferase	KP176698	https://www.ncbi.nlm.nih.gov/nuccore/KP176698	Chang L, Hagel JM, Facchini PJ. Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum. Plant Physiol. 2015;169 (2):1127-40. doi:10.1104/pp.15.01242
GflOMT7	OMT	Glaucium flavum	Papaveraceae	Yes	Blood Root Alkaloids	O-methyltransferase	KP176699	https://www.ncbi.nlm.nih.gov/nuccore/KP176699	Chang L, Hagel JM, Facchini PJ. Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum. Plant Physiol. 2015;169 (2):1127-40. doi:10.1104/pp.15.01243
EcOMT	OMT	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	O-methyltransferase	AB745042.1	https://www.ncbi.nlm.nih.gov/nuccore/AB745042.1	Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Front Plant Sci. 2023;14:1084358. doi:10.3389/fpls.2023.1084358
EcOMT	OMT	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	O-methyltransferase	EU882970.1	https://www.ncbi.nlm.nih.gov/nuccore/EU882970.1	Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Front Plant Sci. 2023;14:1084358. doi:10.3389/fpls.2023.1084358
EcOMT	OMT	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	O-methyltransferase	LC171866.1	https://www.ncbi.nlm.nih.gov/nuccore/LC171866.1	Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Front Plant Sci. 2023;14:1084358. doi:10.3389/fpls.2023.1084358
EcOMT	OMT	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	scoulerine/reticuline O-methyltransferase	LC171865.1	https://www.ncbi.nlm.nih.gov/nuccore/LC171865.1	Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Front Plant Sci. 2023;14:1084358. doi:10.3389/fpls.2023.1084358
Ec4’OMT	OMT	Eschscholzia californica	Papaveraceae	Yes	Chelirubine,Sanguinarine,Macarpine	3'-hydroxy-N-methylcoclaurine-4'-O-methyltransferase	AB745041	https://www.ncbi.nlm.nih.gov/nuccore/AB745041	Bu J, Zhang X, Li Q, et al. Catalytic promiscuity of O-methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids. Hortic Res. 2022;9:uhac152. doi:10.1093/hr/uhac152
PsSOMT1	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	scoulerine-9-O-methyltransferase	JN185323	https://www.ncbi.nlm.nih.gov/nuccore/JN185323	Ozber N, Facchini PJ. Phloem-specific localization of benzylisoquinoline alkaloid metabolism in opium poppy. J Plant Physiol. 2022;271:153641. doi:10.1016/j.jplph.2022.153641
Ps6OMT	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	--	--	--	Pyne ME,Gold ND,Martin VJJ. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera). Metab Eng. 2023;77:162-173. doi:10.1016/j.ymben.2023.03.010
Ps6OMT	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	norcoclaurine 6-O-methyltransferase	AY217335	https://www.ncbi.nlm.nih.gov/nuccore/AY217335	Winzer T,Gazda V,He Z, et al. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science. 2012;336 (6089):1704-8. doi:10.1126/science.1220757
Ps7OMT	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	(R,S)-reticuline 7-O-methyltransferase	AY268893	https://www.ncbi.nlm.nih.gov/nuccore/AY268893	Winzer T,Gazda V,He Z, et al. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science. 2012;336 (6089):1704-8. doi:10.1126/science.1220758
Ps4’OMT	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase	AY217333	https://www.ncbi.nlm.nih.gov/nuccore/AY217333	Winzer T,Gazda V,He Z, et al. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science. 2012;336 (6089):1704-8. doi:10.1126/science.1220759
Ps4’OMT2	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase	AY217334	https://www.ncbi.nlm.nih.gov/nuccore/AY217334	Winzer T,Gazda V,He Z, et al. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science. 2012;336 (6089):1704-8. doi:10.1126/science.1220760
PsN7OMT	OMT	Papaver somniferum	Papaveraceae	Yes	Isoquinolinetype Alkaloids,Protopine,Isocorydine,Papaverine,Morphine,Codeine,Sangulnarine,Chelerythrine,Bocconine,Narcotine,Rhoeadane	norreticuline-7-O-methyltransferase	FJ156103	https://www.ncbi.nlm.nih.gov/nuccore/FJ156103	Winzer T,Gazda V,He Z, et al. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science. 2012;336 (6089):1704-8. doi:10.1126/science.1220761
CyOMT2	OMT	Corydalis yanhusuo	Papaveraceae	Yes	Tetrahydropalmatine	--	--	--	Bu J, Zhang X, Li Q, et al. Catalytic promiscuity of O-methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids. Hortic Res. 2022;9:uhac152. doi:10.1093/hr/uhac152
CyOMT5	OMT	Corydalis yanhusuo	Papaveraceae	Yes	Tetrahydropalmatine	--	--	--	Bu J,Zhang X,Li Q, et al. Catalytic promiscuity of O -methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids. Hortic Res. 2022;9:uhac152. doi:10.1093/hr/uhac152
CyOMT7	OMT	Corydalis yanhusuo	Papaveraceae	Yes	Tetrahydropalmatine	--	--	--	Bu J,Zhang X,Li Q, et al. Catalytic promiscuity of O -methyltransferases from Corydalis yanhusuo leading to the structural diversity of benzylisoquinoline alkaloids. Hortic Res. 2022;9:uhac152. doi:10.1093/hr/uhac152
PsOMT	OMT	Pinus sylvestris	Pinaceae	Yes	Ginsenosides,Polysaccharides	--	KX545295.1	https://www.ncbi.nlm.nih.gov/nuccore/KX545295.1	Paasela T, Lim KJ, Pietiäinen M, Teeri TH. The O-methyltransferase PMT2 mediates methylation of pinosylvin in Scots pine. New Phytol. 2017;214(4):1537-1550. doi:10.1111/nph.14480
PrOMT	OMT	Pinus radiata	Pinoideae	No	Uranium,Cobalt,Radium	O-methyltransferase	U70873.1	https://www.ncbi.nlm.nih.gov/nuccore/U70873.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	O-methyltransferase	M73235.1	https://www.ncbi.nlm.nih.gov/nuccore/M73235.1	Collazo P, Montoliu L, Puigdomènech P, Rigau J. Structure and expression of the lignin O-methyltransferase gene from Zea mays L. Plant Mol Biol. 1992;20(5):857-867. doi:10.1007/BF00027157
ZmCOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	caffeic acid 3-O-methyltransferase	NP_001106047	https://www.ncbi.nlm.nih.gov/protein/NP_001106047	Meng Y, Li J, Liu J, et al. Ploidy effect and genetic architecture exploration of stalk traits using DH and its corresponding haploid populations in maize. BMC Plant Biol. 2016;16:50. doi:10.1186/s12870-016-0742-3
ZmcOmT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	--	--	Meng Y, Li J, Liu J, et al. Ploidy effect and genetic architecture exploration of stalk traits using DH and its corresponding haploid populations in maize. BMC Plant Biol. 2016;16:50. doi:10.1186/s12870-016-0742-3
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	O-methyltransferase	BQ619438.1	https://www.ncbi.nlm.nih.gov/nuccore/BQ619438.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859164.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859164.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859162.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859162.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859161.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859161.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859160.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859160.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859159.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859159.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859158.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859158.1	--
ZmOMT	OMT	Zea mays	Poaceae	Yes	Flavonoids,Polysaccharides,Saponins,Alkaloids,Tannic Acid,Chlorogenic Acid,Volatile Oils,Steroids	--	HB859157.1	https://www.ncbi.nlm.nih.gov/nuccore/HB859157.1	--
SsOMT	OMT	Saccharum spontaneum	Poaceae	Yes	Glycyrrhetinic Acid,Glycyrrhetinic Acid	O-methyltransferase	KU314758.1	https://www.ncbi.nlm.nih.gov/nuccore/KU314758.1	--
SsOMT	OMT	Saccharum spontaneum	Poaceae	Yes	Glycyrrhetinic Acid,Glycyrrhetinic Acid	--	KU314757.1	https://www.ncbi.nlm.nih.gov/nuccore/KU314757.1	--
SsOMT	OMT	Saccharum spontaneum	Poaceae	Yes	Glycyrrhetinic Acid,Glycyrrhetinic Acid	--	KU314756.1	https://www.ncbi.nlm.nih.gov/nuccore/KU314756.1	--
SsOMT	OMT	Saccharum spontaneum	Poaceae	Yes	Glycyrrhetinic Acid,Glycyrrhetinic Acid	--	KU314755.1	https://www.ncbi.nlm.nih.gov/nuccore/KU314755.1	--
SsOMT	OMT	Saccharum spontaneum	Poaceae	Yes	Glycyrrhetinic Acid,Glycyrrhetinic Acid	--	KU314754.1	https://www.ncbi.nlm.nih.gov/nuccore/KU314754.1	--
ShOMT	OMT	Saccharum hybrid	Poaceae	Yes	Organic Acids,Calcium	O-methyltransferase	OL350832.1	https://www.ncbi.nlm.nih.gov/nuccore/OL350832.1	--
AjOMT	OMT	Ardisia japonica	Primulaceae	Yes	1,4-Benzoquinone,Hydroxyethyl Cellulose,Ethanol Extract of Rosa japonica Leaves	O-methyltransferases	OR267196.1	https://www.ncbi.nlm.nih.gov/nuccore/OR267196.1	--
Tf4’OMT	OMT	Thalictrum flavum	Ranunculaceae	Yes	Berberin,β-Sitosterol,N-desmethylthalistyline,5-O-demethylthalistyline	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase	AY610510	https://www.ncbi.nlm.nih.gov/nuccore/AY610510	Becker A, Yamada Y, Sato F. California poppy (Eschscholzia californica), the Papaveraceae golden girl model organism for evodevo and specialized metabolism. Front Plant Sci. 2023;14:1084358. doi:10.3389/fpls.2023.1084358
Tf6OMT	OMT	Thalictrum flavum	Ranunculaceae	Yes	Berberin,β-Sitosterol,N-desmethylthalistyline,5-O-demethylthalistyline	glaucum (S)-norcoclaurine 6-O-methyltransferase	AY610507	https://www.ncbi.nlm.nih.gov/nuccore/AY610507	Menéndez-Perdomo IM, Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13(1):2955. doi:10.1038/s41598-023-29415-0
TfSOMT	OMT	Thalictrum flavum	Ranunculaceae	Yes	Berberin,β-Sitosterol,N-desmethylthalistyline,5-O-demethylthalistyline	glaucum (S)-norcoclaurine 7-O-methyltransferase	AY610512	https://www.ncbi.nlm.nih.gov/nuccore/AY610512	Menéndez-Perdomo IM, Facchini PJ. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Sci Rep. 2023;13(1):2955. doi:10.1038/s41598-023-29415-0
Cc6OMT2	OMT	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	6-O-methyltransferase	MH165876	https://www.ncbi.nlm.nih.gov/nuccore/MH165876	He SM,Liang YL,Cong K, et al. Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species. Front Plant Sci. 2018;9:731. doi:10.3389/fpls.2018.00732
Ct7OMT	OMT	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	norcoclaurine-7OMT	MH165877	https://www.ncbi.nlm.nih.gov/nuccore/MH165877	He SM,Liang YL,Cong K, et al. Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species. Front Plant Sci. 2018;9:731. doi:10.3389/fpls.2018.00733
CtSOMT	OMT	Coptis chinensis	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	scoulerine 9-OMT	MH165874	https://www.ncbi.nlm.nih.gov/nuccore/MH165874	He SM,Liang YL,Cong K, et al. Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species. Front Plant Sci. 2018;9:731. doi:10.3389/fpls.2018.00734
Cj4’OMT	OMT	Coptis japonica	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	3'-hydroxy-N-methy lcoclaurine 4'-O-methyltransferase	D29812	https://www.ncbi.nlm.nih.gov/nuccore/D29812	Inui T,Kawano N,Shitan N, et al. Improvement of benzylisoquinoline alkaloid productivity by overexpression of 3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase in transgenic Coptis japonica plants. Biol Pharm Bull. 2012;35 (5):650-9. doi:10.1248/bpb.35.651
Cj6OMT	OMT	Coptis japonica	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase	D29811	https://www.ncbi.nlm.nih.gov/nuccore/D29811	Inui T,Kawano N,Shitan N, et al. Improvement of benzylisoquinoline alkaloid productivity by overexpression of 3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase in transgenic Coptis japonica plants. Biol Pharm Bull. 2012;35 (5):650-9. doi:10.1248/bpb.35.650
CjCoOMT	OMT	Coptis japonica	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	columbamine O-methyltransferase	AB073908	https://www.ncbi.nlm.nih.gov/nuccore/AB073908	Inui T,Kawano N,Shitan N, et al. Improvement of benzylisoquinoline alkaloid productivity by overexpression of 3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase in transgenic Coptis japonica plants. Biol Pharm Bull. 2012;35 (5):650-9. doi:10.1248/bpb.35.652
CjSOMT	OMT	Coptis japonica	Ranunculaceae	Yes	Berberine,Berberine,Isoberberine,Rutin	scoulerine 9-O-methyltransferase	D29809	https://www.ncbi.nlm.nih.gov/nuccore/D29809	Inui T,Kawano N,Shitan N, et al. Improvement of benzylisoquinoline alkaloid productivity by overexpression of 3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase in transgenic Coptis japonica plants. Biol Pharm Bull. 2012;35 (5):650-9. doi:10.1248/bpb.35.653
TtOMT	OMT	Thalictrum tuberosum	Ranunculaceae	Yes	Thalidasine Ⅰ,Thalifoetidine Ⅱ	catechol O-methyltransferase	AF064696.2	https://www.ncbi.nlm.nih.gov/nuccore/AF064696.2	Frick S, Kutchan TM. Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J. 1999;17(4):329-339. doi:10.1046/j.1365-313x.1999.00379.x
TtOMT	OMT	Thalictrum tuberosum	Ranunculaceae	Yes	Thalidasine Ⅰ,Thalifoetidine Ⅱ	O-methyltransferase	AF064697.1	https://www.ncbi.nlm.nih.gov/nuccore/AF064697.1	Frick S, Kutchan TM. Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J. 1999;17(4):329-339. doi:10.1046/j.1365-313x.1999.00379.x
TtOMT	OMT	Thalictrum tuberosum	Ranunculaceae	Yes	Thalidasine Ⅰ,Thalifoetidine Ⅱ	catechol O-methyltransferase	AF064695.1	https://www.ncbi.nlm.nih.gov/nuccore/AF064695.1	Frick S, Kutchan TM. Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J. 1999;17(4):329-339. doi:10.1046/j.1365-313x.1999.00379.x
TtOMT	OMT	Thalictrum tuberosum	Ranunculaceae	Yes	Thalidasine Ⅰ,Thalifoetidine Ⅱ	catechol O-methyltransferase	AF064694.1	https://www.ncbi.nlm.nih.gov/nuccore/AF064694.1	Frick S, Kutchan TM. Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J. 1999;17(4):329-339. doi:10.1046/j.1365-313x.1999.00379.x
TtOMT	OMT	Thalictrum tuberosum	Ranunculaceae	Yes	Thalidasine Ⅰ,Thalifoetidine Ⅱ	catechol O-methyltransferase	AF064693.1	https://www.ncbi.nlm.nih.gov/nuccore/AF064693.1	Frick S, Kutchan TM. Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J. 1999;17(4):329-339. doi:10.1046/j.1365-313x.1999.00379.x
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	KX450222.1	https://www.ncbi.nlm.nih.gov/nuccore/KX450222.1	Fu X, Cheng S, Zhang Y, et al. Differential responses of four biosynthetic pathways of aroma compounds in postharvest strawberry (Fragaria×ananassa Duch.) under interaction of light and temperature. Food Chem. 2017;221:356-364. doi:10.1016/j.foodchem.2016.10.082
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322659.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322659.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322657.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322657.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322656.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322656.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322655.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322655.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322654.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322654.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322653.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322653.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322652.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322652.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322651.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322651.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
FXaOMT	OMT	Fragaria ananassa	Rosaceae	Yes	Carotenoids,Calcium,Coumarins,Saponins,Organic Acids	O-methyltransferase	JQ322658.1	https://www.ncbi.nlm.nih.gov/nuccore/JQ322658.1	Zorrilla-Fontanesi Y, Rambla JL, Cabeza A, et al. Genetic analysis of strawberry fruit aroma and identification of O-methyltransferase FaOMT as the locus controlling natural variation in mesifurane content. Plant Physiol. 2012;159(2):851-870. doi:10.1104/pp.111.188318
MtOMT	OMT	Macromeles tschonoskii	Rosaceae	Yes	Saponins	--	LC437822.1	https://www.ncbi.nlm.nih.gov/nuccore/LC437822.1	Aizawa M. An Overlooked Tree Species, Micromeles calocarpa (Rehder) M. Aizawa (Rosaceae), from Central Japan[J]. Acta phytotaxonomica et geobotanica: APG, 2021;72(1). doi:10.18942/apg.202007.
MtOMT	OMT	Macromeles tschonoskii	Rosaceae	Yes	Saponins	--	LC437874.1	https://www.ncbi.nlm.nih.gov/nuccore/LC437874.1	--
MtOMT	OMT	Macromeles tschonoskii	Rosaceae	Yes	Saponins	ribulose-1,5-bisphosphate carboxylase	LC437831.1	https://www.ncbi.nlm.nih.gov/nuccore/LC437831.1	--
PmOMT1	OMT	Prunus mume	Rosaceae	Yes	Chlorogenic Acid,Isoquercitrin,Hyperoside	O-methyltransferase	GU339212.1	https://www.ncbi.nlm.nih.gov/nuccore/GU339212.1	--
PtOMT1	OMT	Populus tremuloides	Salicaceae	Yes	Lignin	caffeic acid/5-hydroxyferulic acid O-methyltransferase	U13171.1	https://www.ncbi.nlm.nih.gov/nuccore/U13171.1	Tsai CJ, Podila GK, Chiang VL. Nucleotide sequence of a Populus tremuloides gene encoding bispecific caffeic acid/5-hydroxyferulic acid O-methyltransferase. Plant Physiol. 1995;107(4):1459. doi:10.1104/pp.107.4.1459
BpOMT	OMT	Bergenia purpurascens	Saxifragaceae	Yes	Condensed Tannins of Bergenin,Catechins,Arbutin Glycosides	O-methyltransferases	OR267195.1	https://www.ncbi.nlm.nih.gov/nuccore/OR267195.1	--
StOMT	OMT	Solanum tuberosum	Solanaceae	Yes	Carbohydrates,Cellulose	--	X99853.1	https://www.ncbi.nlm.nih.gov/nuccore/X99853.1	--
AbPMT	OMT	Atropa belladonna	Solanaceae	Yes	Hyoscyamine,Atropine,Scopolamine,Belladonin	putrescine methyltransferase	ON647441.1	https://www.ncbi.nlm.nih.gov/nuccore/ON647441.1	Xia K,Liu X,Zhang Q, et al. Promoting scopolamine biosynthesis in transgenic Atropa belladonna plants with pmt and h6h overexpression under field conditions. Plant Physiol Biochem. 2016;106:46-53. doi:10.1016/j.plaphy.2016.04.034
NtOMT1	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	O-methyltransferase	M84411.1	https://www.ncbi.nlm.nih.gov/nuccore/M84411.1	Jaeck E, Dumas B, Geoffroy P, et al. Regulation of enzymes involved in lignin biosynthesis: induction of O-methyltransferase mRNAs during the hypersensitive reaction of tobacco to tobacco mosaic virus. Mol Plant Microbe Interact. 1992;5(4):294-300. doi:10.1094/mpmi-5-294
NtOMT	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	O-methyltransferase	X74453.1	https://www.ncbi.nlm.nih.gov/nuccore/X74453.1	Jaeck E, Martz F, Stiefel V, Fritig B, Legrand M. Expression of class I O-methyltransferase in healthy and TMV-infected tobacco. Mol Plant Microbe Interact. 1996;9(8):681-688. doi:10.1094/mpmi-9-0681
NtOMT	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	O-methyltransferase	X74452.1	https://www.ncbi.nlm.nih.gov/nuccore/X74452.1	Jaeck E, Martz F, Stiefel V, Fritig B, Legrand M. Expression of class I O-methyltransferase in healthy and TMV-infected tobacco. Mol Plant Microbe Interact. 1996;9(8):681-688. doi:10.1094/mpmi-9-0681
NtOdOMT	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	o-diphenol-O-methyltransferase	X71430.1	https://www.ncbi.nlm.nih.gov/nuccore/X71430.1	Pellegrini L, Geoffroy P, Fritig B, Legrand M. Molecular cloning and expression of a new class of ortho-diphenol-O-methyltransferases induced in tobacco (Nicotiana tabacum L.) leaves by infection or elicitor treatment. Plant Physiol. 1993;103(2):509-517. doi:10.1104/pp.103.2.509
NtOMT1	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	orthomethyl transferase	AJ937843.1	https://www.ncbi.nlm.nih.gov/nuccore/AJ937843.1	Szatmari A, Ott PG, Varga GJ, et al. Characterisation of basal resistance (BR) by expression patterns of newly isolated representative genes in tobacco. Plant Cell Rep. 2006;25(7):728-740. doi:10.1007/s00299-005-0110-5
Nt3OMT	OMT	Nicotiana tabacum	Solanaceae	Yes	Nicotine	--	--	--	Szatmari A, Ott PG, Varga GJ, et al. Characterisation of basal resistance (BR) by expression patterns of newly isolated representative genes in tobacco. Plant Cell Rep. 2006;25(7):728-740. doi:10.1007/s00299-005-0110-5
VaAOMT	OMT	Vitis amurensis	Vitaceae	Yes	Ampelopsin B,Myricetin,Kaempferol,Luteolin	anthocyanin-O-methyltransferase	GU237132.1	https://www.ncbi.nlm.nih.gov/nuccore/GU237132.1	--
S9OMT	OMT	Thalictrum flavum	Ranunculaceae	--	--	--	--	--	Li Y,Li S,Thodey K, et al. Complete biosynthesis of noscapine and halogenated alkaloids in yeast. Proc Natl Acad Sci U S A. 2018;115 (17):E3922-E3931. doi:10.1073/pnas.1721469115
4'OMT	OMT	Papaver somniferum	Papaveraceae	Yes	--	--	--	--	Li Y,Li S,Thodey K, et al. Complete biosynthesis of noscapine and halogenated alkaloids in yeast. Proc Natl Acad Sci U S A. 2018;115 (17):E3922-E3931. doi:10.1073/pnas.1721469116
CNMT	OMT	--	--	--	--	--	--	--	Li Y,Li S,Thodey K, et al. Complete biosynthesis of noscapine and halogenated alkaloids in yeast. Proc Natl Acad Sci U S A. 2018;115 (17):E3922-E3931. doi:10.1073/pnas.1721469117
EnMT4	OMT	--	--	--	--	--	--	--	Wang YJ,Huang JP,Tian T, et al. Discovery and Engineering of the Cocaine Biosynthetic Pathway. J Am Chem Soc. 2022;144 (48):22000-22007. doi:10.1021/jacs.2c09091
MhrOMT	OMT	Malus hybrid rootstock	--	--	--	O-methyltransferase	GO502189.1	https://www.ncbi.nlm.nih.gov/nuccore/GO502189.1	--

Gene (Alkaloids)